The new SBI software is a reliable tool to exclude active bleeding and/or major lesions but analysis of the CE video by a trained investigator is still important for the detection of lesions responsible for past bleeding.Ĥ0Ar/39Ar dating of the Mumbai tholeiites and Panvel flexure: intense 62.5 Ma onshore-offshore Deccan magmatism during India-Laxmi Ridge-Seychelles breakup ROC analysis revealed 51.0 SBI markings being the optimal cutoff for active versus no bleeding (sensitivity 79.1%, specificity 90.4%, misclassification of 15.3%). All patients with active bleeding were detected by SBI (sensitivity 100%, specificity 13%). SBI turned positive in 179 patients, whereas the investigator detected active bleeding in 42 cases. When major bleeding was diagnosed by the investigator (n = 29), SBI detected a mean of 46.6 SBI-positive markings. Thirteen patients showed investigator-detected minor bleeding with mean SBI findings of 36 positive screenshots per record. In 20 cases, neither SBI nor the human investigator detected abnormalities. One hundred and thirty-seven of these 157 cases provided at least one SBI marking and a mean of 18.4 positive SBI markings per record were found. In 157/199 cases, no sign of active bleeding or altered blood was detected. The findings of an independent investigator were correlated to SBI findings and a number of SBI markings were analyzed by a receiver operating characteristic (ROC). The second-generation PillCam SB 2 capsule was used for detection of (1) luminal blood content and (2) potentially responsible small bowel lesions. This is a retrospective analysis of all patients (199) who attended our clinic for CE from June 2008 through March 2013. The objective was to analyze specificity and sensitivity of the SBI using the second small bowel capsule generation for the detection of active bleeding. The "suspected blood indicator" ( SBI) offers an automated detection of active small bowel bleeding but validity of this technique is unknown. Tal, Andrea Oliver Filmann, Natalie Makhlin, Konstantin Hausmann, Johannes Friedrich-Rust, Mireen Herrmann, Eva Zeuzem, Stefan Albert, Jörg GĬapsule endoscopy (CE) is the gold standard to diagnose small bowel bleeding. The capsule endoscopy "suspected blood indicator" ( SBI) for detection of active small bowel bleeding: no active bleeding in case of negative SBI.
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